Search results for "Pressure support"

showing 10 items of 12 documents

Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: Study protocol for a pilot randomized controlled trial, the PROT…

2018

Background Adding cyclic short sustained inflations (sigh) to assisted ventilation yields optimizes lung recruitment, decreases heterogeneity and reduces inspiratory effort in patients with acute hypoxemic respiratory failure (AHRF). These findings suggest that adding sigh to pressure support ventilation (PSV) might decrease the risk of lung injury, shorten weaning and improve clinical outcomes. Thus, we conceived a pilot trial to test the feasibility of adding sigh to PSV (the PROTECTION study). Methods PROTECTION is an international randomized controlled trial that will be conducted in 23 intensive care units (ICUs). Patients with AHRF who have been intubated from 24 h to 7 days and under…

procedurePressure supportTime Factorsgenetic structuresbreathingmedicine.medical_treatmentMedicine (miscellaneous)Pilot Projects[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractintensive care unitlaw.inventionPositive-Pressure RespirationStudy Protocol0302 clinical medicineMechanical ventilationRandomized controlled triallawtime factorClinical endpointpatient safetyMulticenter Studies as TopicPharmacology (medical)030212 general & internal medicinerandomized controlled trial (topic)Intervention study; Mechanical ventilation; Positive-pressure ventilation; Pressure support; Recruitment; Sigh; Ventilator-induced lung injury; Weaning; Feasibility Studies; Humans; Hypoxia; Intubation Intratracheal; Lung; Multicenter Studies as Topic; Pilot Projects; Positive-Pressure Respiration; Recovery of Function; Respiratory Insufficiency; Time Factors; Treatment Outcome; Randomized Controlled Trials as Topic; Medicine (miscellaneous); Pharmacology (medical)HypoxiaLungpathophysiologyendotracheal intubationRandomized Controlled Trials as TopicVentilator-induced lung injurylcsh:R5-920Intervention studyadultpilot studyfeasibility studytreatment outcome Feasibility Studie3. Good healthTreatment OutcomeAnesthesiapositive end expiratory pressureBreathingmulticenter study (topic)oxygenationRecruitmentlcsh:Medicine (General)Respiratory Insufficiencyrespiratory tract intubationcirculatory and respiratory physiologyHumanextubationPressure support ventilationWeaningLung injuryArticleSpontaneous breathing trialNO03 medical and health sciencesIntensive care[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]medicineIntubation IntratrachealHumanscontrolled studyPilot ProjectSightreatment failureMechanical ventilationhypoxemiapressure support ventilationtreatment durationbusiness.industrylung inflationrespiratory failureconvalescenceRecovery of Functionmajor clinical studymortalitywater acute respiratory failurehospital dischargeIntratracheal030228 respiratory systemrandomized controlled trialFeasibility StudiesbusinessPositive-pressure ventilationIntubationclinical protocol
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Tidal Volume Estimation during Helmet Noninvasive Ventilation: an Experimental Feasibility Study

2019

AbstractWe performed a bench (BS) and human (HS) study to test the hypothesis that estimation of tidal volume (VT) during noninvasive helmet pressure support ventilation (nHPSV) would be possible using a turbine driven ventilator (TDV) coupled with an intentional leak single-limb vented circuit. During the BS a mannequin was connected to a lung simulator (LS) and at different conditions of respiratory mechanics, positive end expiratory pressure (PEEP) levels and leaks (30, 50 and 80 L/min). All differences were within the 95% limits of agreement (LoA) in all conditions in the Bland-Altman plot. The overall bias (difference between VT measured by TDV and LS) was 35 ml (95% LoA 10 to 57 ml), …

AdultMaleLeakmedicine.medical_specialtylcsh:MedicineSettore MED/41 - AnestesiologiaPressure support ventilationTherapeuticsRespiratory physiologyManikinsArticlePositive-Pressure Respiration03 medical and health sciences0302 clinical medicineInternal medicineHealthy volunteersTidal VolumemedicineHumanslcsh:SciencePositive end-expiratory pressureTidal volumeMouthpieceVentilators Mechanicalacute respiratory failureMultidisciplinarybusiness.industrylcsh:RhelmetReproducibility of Resultsnoninvasive ventilation030208 emergency & critical care medicineEquipment DesignHealthy Volunteers030228 respiratory systemPreclinical researchRespiratory MechanicsCardiologyFeasibility Studieslcsh:QFemaleHead Protective DevicesNoninvasive ventilationbusinessScientific Reports
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Influence of different interfaces on synchrony during pressure support ventilation in a pediatric setting: a bench study

2015

BACKGROUND: In adults and children, patient-ventilator synchrony is strongly dependent on both the ventilator settings and interface used in applying positive pressure to the airway. The aim of this bench study was to determine whether different interfaces and ventilator settings may influence patient-ventilator interaction in pediatric models of normal and mixed obstructive and restrictive respiratory conditions. METHODS: A test lung, connected to a pediatric mannequin using different interfaces (endotracheal tube [ETT], face mask, and helmet), was ventilated in pressure support ventilation mode testing 2 ventilator settings (pressurization time [Timepress]50%/cycling-off flow threshold [T…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyRespiratory rateface maskPositive pressurePressure support ventilationRespiratory physiologyCritical Care and Intensive Care MedicineManikinsManikinPositive-Pressure Respirationendotracheal tubepatient-ventilator interactionSettore MED/41 - ANESTESIOLOGIAmedicineIntubation IntratrachealHumansIntensive care medicineChildInteractive Ventilatory Supportpressure-support ventilationLungVentilators MechanicalMaskRespiratory MechanicHead Protective Devicebusiness.industryRespirationMaskshelmetnoninvasive ventilationGeneral Medicinemedicine.anatomical_structureAnesthesiaBreathingRespiratory MechanicsHead Protective DevicesAirwaybusinessInteractive Ventilatory SupportHuman
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Sigh in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: the PROTECTION pilot randomized clinical trial

2021

Background: Sigh is a cyclic brief recruitment manoeuvre: previous physiological studies showed that its use could be an interesting addition to pressure support ventilation to improve lung elastance, decrease regional heterogeneity and increase release of surfactant. Research question: Is the clinical application of sigh during pressure support ventilation (PSV) feasible? Study design and methods: We conducted a multi-center non-inferiority randomized clinical trial on adult intubated patients with acute hypoxemic respiratory failure or acute respiratory distress syndrome undergoing PSV. Patients were randomized to the No Sigh group and treated by PSV alone, or to the Sigh group, treated b…

pressure supportventilationsighARDSmechanical ventilationfeasibility
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Compliance to ventilatory treatment in a cohort of patients on home CPAP or NIV: analysis by diagnosis, treatment type, and comorbidities

2019

Background: Patients on home continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) show large variability in compliance to treatment. Aim: To identify predictors of poor compliance, we evaluated compliance to treatment in patients with obstructive sleep apnea (OSA), obesity hypoventilation syndrome (OHS), and OSA-chronic obstructive pulmonary disease (COPD) overlap syndrome. Methods: We analyzed clinical and compliance data provided by a single home care provider, in 602 patients (n=442 OSA, males (M) 308; 38 OHS M=15, and 122 overlap M=111) on home CPAP/NIV in the province of Agrigento, Italy, after one year of treatment. The following variables were considered: age, …

Obesity hypoventilation syndromeCOPDmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentOverlap syndromePressure support ventilationmedicine.diseaserespiratory tract diseasesObstructive sleep apneaInternal medicineCohortmedicineContinuous positive airway pressurebusinessBody mass indexSleep and control of breathing
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New modes in non-invasive ventilation

2016

IF 2.536; International audience; Non-invasive ventilation is useful to treat some forms of respiratory failure. Hence, the number of patients receiving this treatment is steadily increasing. Considerable conceptual and technical progress has been made in recent years by manufacturers concerning this technique. This includes new features committed to improve its effectiveness as well as patient-ventilator interactions. The goal of this review is to deal with latest advances in ventilatory modes and features available for non-invasive ventilation. We present a comprehensive analysis of new modes of ventilator assistance committed to treat respiratory failure (hybrid modes) and central and co…

Pulmonary and Respiratory MedicineComplex sleep apneamedicine.medical_specialtyCentral sleep apneaAdaptive servo ventilation[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/PediatricsCheyne-stokes respirationReview030204 cardiovascular system & hematologyPositive airway pressureRespiratory failure[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractAssured pressure support03 medical and health sciences0302 clinical medicinemedicineNeurally adjusted ventilatory assistVentilatory modesHumansIntensive care medicineObstructive pulmonary-diseaseComplex sleep-apnea[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/PediatricsNoninvasive Ventilationbusiness.industryDiaphragm electrical-activityNon invasive ventilationmedicine.diseaseNeuro adjusted ventilatory assistClinical PracticeRandomized controlled-trialAdaptative servo ventilationChronic heart-failure030228 respiratory systemRespiratory failurePediatrics Perinatology and Child HealthBreathingCentral sleep apneabusinessRespiratory InsufficiencyImproves cardiac-function[ SDV.MHEP.PSR ] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract
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Sigh in Patients With Acute Hypoxemic Respiratory Failure and ARDS

2021

Background Sigh is a cyclic brief recruitment maneuver: previous physiologic studies showed that its use could be an interesting addition to pressure support ventilation to improve lung elastance, decrease regional heterogeneity, and increase release of surfactant. Research Question Is the clinical application of sigh during pressure support ventilation (PSV) feasible? Study Design and Methods We conducted a multicenter noninferiority randomized clinical trial on adult intubated patients with acute hypoxemic respiratory failure or ARDS undergoing PSV. Patients were randomized to the no-sigh group and treated by PSV alone, or to the sigh group, treated by PSV plus sigh (increase in airway pr…

Pulmonary and Respiratory MedicineARDSbusiness.industryPressure support ventilationCritical Care and Intensive Care Medicinemedicine.diseaseSpontaneous breathing triallaw.invention03 medical and health sciences0302 clinical medicine030228 respiratory systemRandomized controlled triallawAnesthesiaBreathingMedicine030212 general & internal medicineCardiology and Cardiovascular MedicinebusinessRespiratory minute volumePositive end-expiratory pressureTidal volumeChest
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Comparative bench study evaluation of different infant interfaces for non-invasive ventilation

2018

Abstract Background To compare, in terms of patient-ventilator interaction and performance, a new nasal mask (Respireo, AirLiquide, FR) with the Endotracheal tube (ET) and a commonly used nasal mask (FPM, Fisher and Paykel, NZ) for delivering Pressure Support Ventilation (PSV) in an infant model of Acute Respiratory Failure (ARF). Methods An active test lung (ASL 5000) connected to an infant mannequin through 3 different interfaces (Respireo, ET and FPM), was ventilated with a standard ICU ventilator set in PSV. The test lung was set to simulate a 5.5 kg infant with ARF, breathing at 50 and 60 breaths/min). Non-invasive ventilation (NIV) mode was not used and the leaks were nearly zero. Res…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyAcute respiratory failure; Bench test; Infant mask; Mechanical ventilation; Non invasive ventilation; Patient-ventilator interactionRespiratory ratemedicine.medical_treatmentPressure support ventilationAcute respiratory failureManikinsBench test03 medical and health sciences0302 clinical medicineMechanical ventilationRespiratory Rate030225 pediatricsInternal medicineSettore MED/41 - ANESTESIOLOGIAIntubation IntratrachealTidal VolumeMedicineNon-invasive ventilationHumansTidal volumePatient-ventilator interactionMonitoring PhysiologicWork of BreathingMechanical ventilationlcsh:RC705-779LungNoninvasive Ventilationbusiness.industryMasksInfantNon invasive ventilationlcsh:Diseases of the respiratory systemAcute respiratory failure; Bench test; Infant mask; Mechanical ventilation; Non invasive ventilation; Patient-ventilator interaction; Pulmonary and Respiratory Medicinemedicine.anatomical_structure030228 respiratory systemVolume (thermodynamics)ItalyAcute DiseaseBreathingCardiologyInfant maskbusinessRespiratory InsufficiencyResearch ArticleBMC Pulmonary Medicine
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Chest wall mechanics during pressure support ventilation.

2005

Introduction During pressure support ventilation (PSV) a part of the breathing pattern is controlled by the patient, and synchronization of respiratory muscle action and the resulting chest wall kinematics is a valid indicator of the patient's adaptation to the ventilator. The aim of the present study was to analyze the effects of different PSV settings on ventilatory pattern, total and compartmental chest wall kinematics and dynamics, muscle pressures and work of breathing in patients with acute lung injury. Method In nine patients four different levels of PSV (5, 10, 15 and 25 cmH2O) were randomly applied with the same level of positive end-expiratory pressure (10 cmH2O). Flow, airway ope…

AdultMaleResearchMiddle AgedPressure support ventilation; Chest; Respiratory musclesPressure support ventilationPositive-Pressure RespirationRespiratory musclesRespiratory MechanicsChestHumansFemaleRespiratory InsufficiencyThoracic WallAged
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The right interface for the right patient in noninvasive ventilation: a systematic review

2022

Introduction Research in the field of noninvasive ventilation (NIV) has contributed to the development of new NIV interfaces. However, interface tolerance plays a crucial role in determining the beneficial effects of NIV therapy. Areas covered This systematic review explores the most significant scientific research on NIV interfaces, with a focus on the potential impact that their design might have on treatment adherence and clinical outcomes. The rationale on the choice of the right interface among the wide variety of devices that are currently available is discussed here. Expert opinion The paradigm 'The right mask for the right patient' seems to be difficult to achieve in real life. Rang…

Pulmonary and Respiratory Medicinepressure support ventilationhelmettotal face maskPublic Health Environmental and Occupational Healthnoninvasive ventilationInterfacemouthpiecenasal pillowsmaskhybrid maskoronasal maskCPAPNIVoral masknasal maskImmunology and Allergycustom maskcontinuous positive pressure ventilation
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